Senior Scientist / Principal Scientist, Bioanalytical Sciences

Location: Cambridge, MA or Copenhagen, Denmark Reporting to: Director, Bioanalytics About Hemab Hemab is building preventative treatments for serious, underserved bleeding disorders. These are therapies designed to work with the body's own biology and stop bleeds before they start, instead of treating them after they happen. We're patient-first, science-led and clinical-stage - with a pipeline that takes different scientific approaches to different patient needs. We went public via our 2026 IPO, and we're scaling across two homes: Cambridge, MA, USA, and Copenhagen, Denmark. The role Good bioanalytical science helps us understand how our medicines behave in the body and make informed decisions about their development. You'll lead bioanalytical work for one or more development programs, from nonclinical studies through clinical development. Working with external laboratories and colleagues across Hemab, you'll make sure our PK, immunogenicity and biomarker data are reliable, delivered when needed and ready for regulatory review. The role can be appointed at Senior Scientist or Principal Scientist level, depending on your experience and scope of independent leadership. What you'll do

• Own the bioanalytical strategy and delivery for assigned development programs.
• Lead outsourced PK, ADA/NAb and PD/biomarker assay development, transfer, validation and sample analysis.
• Manage CRO relationships, including scientific oversight, timelines, budgets and resolving issues before they affect studies.
• Review bioanalytical plans, validation reports and study data against ICH M10, FDA/EMA guidance and GLP/GCP expectations.
• Work with Clinical Operations, central laboratories and study sites to get clinical samples collected, shipped and reconciled correctly.
• Investigate assay failures, unexpected results and deviations, and agree practical solutions with external laboratories.
• Contribute bioanalytical content to regulatory submissions and responses to health authority questions.
• Help develop consistent, useful ways of working as Hemab's portfolio grows.

What you'll bring to Hemab

• Demonstrated bioanalytical experience supporting biologics through nonclinical and clinical development.
• Experience overseeing outsourced assay development, validation and clinical sample analysis.
• Strong scientific knowledge of ligand-binding assays and LC-MS/MS, including troubleshooting with external laboratories.
• Working knowledge of ICH M10, immunogenicity guidance and GLP/GCP requirements.
• Experience working with clinical sample logistics, bioanalytical data and cross-functional study teams.
• Ability to take ownership of scientific decisions, manage competing priorities and communicate clearly.

Nice to have

• Experience preparing bioanalytical content for regulatory submissions.
• Experience with multinational clinical trials, rare diseases or bleeding disorders.
• Experience establishing bioanalytical ways of working in a growing biotech company.
• For Principal Scientist, you'll also bring demonstrated experience independently leading program-level bioanalytical strategy and influencing development decisions.

What to expect, honestly Hemab is still building a lot of its own structure. Systems here tend to get created as we need them, not handed down in advance. Whoever takes this role will likely build some of their own process instead of inheriting a finished one. We work across two hubs and multiple time zones - bridging that well takes real, deliberate effort. And because we're growing quickly, priorities can shift with less notice than they would at a larger, more established company. Much of our bioanalytical work happens through external partners. You'll be accountable for the science and the quality of the data, even when the experiments happen in someone else's laboratory. That means staying close to the detail, asking difficult questions when something doesn't look right and being prepared to work through problems yourself. We're also still building parts of how we work. Some frameworks are established; others will need your input. You'll have room to shape them, but you won't always have a ready-made answer or a large team to take things forward. Why Hemab At Hemab, your work ultimately connects back to something simple. People living with serious bleeding disorders get something they've never had before - the chance to prevent a bleed, instead of reacting to one after it happens. You'll be joining at a stage where individual decisions still carry real weight, and where your work can help turn promising science into a preventative treatment that actually reaches patients. How we treat our people is meant to be an extension of how we think about patients: with care, honesty, and respect. We're still building the consistency to back that up across every hiring process, every time. We'd say that plainly instead of pretending otherwise. If any part of your experience with us falls short of it, tell us. Hemab builds balanced candidate slates and assesses everyone against a single standard. If you need a reasonable adjustment at any stage of the hiring process, please tell us. Equal Employment Opportunity Hemab Therapeutics is proud to be an equal opportunity employer, seeking to create a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, creed, gender, national origin, age, disability, veteran status, pregnancy, sex, marital status, gender expression or identity, genetic information, sexual orientation, citizenship, or any other legally protected class.